Investigations of seborrheic dermatitis. Part I. The role of selected cytokines in the pathogenesis of seborrheic dermatitis

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Investigations of seborrheic dermatitis. Part I. The role of selected cytokines in the pathogenesis of seborrheic dermatitis.

INTRODUCTION The etiology of seborrheic dermatitis is not fully understood. It has been observed that a number of anascogenic yeasts of Malassezia spp. is related to the intensity of the symptoms. The aim of the study is to measure the concentration of selected inflammatory factors IL-2, IL-4, IFN-γ and TNF-α in the serum by an immunoenzymatic method, as well as to confirm the relationship betw...

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Investigations of seborrheic dermatitis. Part II. Influence of itraconazole on the clinical condition and the level of selected cytokines in seborrheic dermatitis.

INTRODUCTION The pathogenesis of seborrheic dermatitis has not been fully elucidated. A number of anascogenic yeasts of Malassezia spp. appear to be involved in the intensity of the symptoms. The purpose of the study is to evaluate the levels of selected inflammatory cytokines, IL-2, IL-4, IFN-γ and TNF-α, in the serum after treatment with itraconazole. MATERIAL/METHODS Sixty-six subjects wer...

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Seborrheic dermatitis is a common condition that usually appears as simple dandruff. It may affect the scalp, the central part of the face and the anterior portion of the chest, as well as flexural creases of the arms, legs and groin. It occurs most often in infants and in adults between 30 and 60 years of age. Patients with acquired immunodeficiency syndrome may have particularly resistant cas...

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From the Department of Dermatology (L.N.) and Centro Studi Gruppo Italiano Studi Epidemiologici in Dermatologia (L.N., A.R.), Ospedali Riuniti, Bergamo; and the Section of Dermatology, Department of Endocrinologic and Medical Sciences, University of Genoa, Genoa (A.R.) — both in Italy. Address reprint requests to Dr. Naldi at Centro Studi GISED, Ospedali Riuniti, Largo Barozzi 1, 24128 Bergamo,...

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Seborrheic dermatitis.

Seborrheic dermatitis is a common chronic inflammatory skin condition, characterized by scaling and poorly defined erythematous patches. It may be associated with pruritus, and it primarily affects sebum-rich areas, such as the scalp, face, upper chest, and back. Although its pathogenesis is not completely understood, some postulate that the condition results from colonization of the skin of af...

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ژورنال

عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej

سال: 2012

ISSN: 1732-2693

DOI: 10.5604/17322693.1019642